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Regenerative Therapy Definition and Types
Regenerative therapy is a cellular-level therapy that aims to improve the function of damaged or diseased tissue or organs by introducing cells to replace or repair damaged cells. Today, regenerative therapies are being recognized for their therapeutic potential for a wide variety of medical conditions across a range of specialties, including orthopedics, rheumatology, cardiology, neurology, immunology, and much more.
Because of their ability to differentiate into cells that carry out the roles needed in a variety of bodily functions; cellular allografts are an essential regenerative tool. When these allografts are introduced into damaged tissue or organ, they have the ability to evolve and carry out necessary functions, repairing or compensating for the damaged cells. As a minimally invasive process, regenerative therapy harnesses the natural capabilities of regenerative allografts and the body’s own ability to heal, providing an opportunity to avoid painful and invasive procedures.
Because of their ability to differentiate into cells that carry out the roles needed in a variety of bodily functions; cellular allografts are an essential regenerative tool. When these allografts are introduced into damaged tissue or organ, they have the ability to evolve and carry out necessary functions, repairing or compensating for the damaged cells. As a minimally invasive process, regenerative therapy harnesses the natural capabilities of regenerative allografts and the body’s own ability to heal, providing an opportunity to avoid painful and invasive procedures.
Scope of Regenerative Therapy
Cell allografts, that occur naturally in the body, are “naive” or unspecialized. This means that, based on cues from their environment, these cells have the ability to transform into and assume the functions of a variety of different cells and cell types in the body. The ability to mature in a context-specific way is the key to the vast potential of cells in regenerative therapies. When introduced into damaged tissue, the cells can specialize and carry out their necessary functions in that particular area, potentially improving symptoms and function.
Scope of Regenerative Therapy
Cell allografts, that occur naturally in the body, are “naive” or unspecialized. This means that, based on cues from their environment, these cells have the ability to transform into and assume the functions of a variety of different cells and cell types in the body. The ability to mature in a context-specific way is the key to the vast potential of cells in regenerative therapies. When introduced into damaged tissue, the cells can specialize and carry out their necessary functions in that particular area, potentially improving symptoms and function.
What Makes MSC's Different
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Migration
MSCs have a special ability to move to specific tissues, going where the body needs them most. This means that the cells can be injected into the bloodstream to then move on their own to the affected area.
Repair
In the case of tissue damage, MSCs have the ability to release growth factors and specialize into a number of tissue cell types that allow for the tissue to be regenerated.
Immunomodulation
When foreign cells are introduced in the body, the concern is that they will often generate an immune response. Because MSCs express very few antigens on their surfaces that can generate an immune response (like MHCI or MHCII), they do not elicit a reaction from the patient’s immune system T-cells, making them safe to use.
Reduction of Inflammation
MSCs reduce the signal cells that promote inflammation (like TNF-alpha and TNF-gamma). While this is another function that helps them to avoid the immune response, it is also essential to the cells’ utility in chronic and autoimmune diseases characterized by inflammation.
Where Do Our Products Come From
While regenerative cells are found throughout the body, the cells used in medicine today may be derived from four different sources: umbilical cord tissue, embryonic tissue, bone marrow aspirate, and adipose tissue. However, some sources have their drawbacks. Embryonic cells raise ethical concerns, while bone marrow and adipose tissue-derived products can only be retrieved through invasive surgical procedures and have a significantly lower yield.
Considering this, BioGenix uses exclusively umbilical cord-derived products. Umbilical cord tissue retrieval, which takes place immediately after the umbilical cord is cut upon delivery, is non-invasive and ethically sound. In addition, umbilical cord tissue products have the highest product yield and are the best source of growth factors and cytokines that have an important role in regenerative therapies.
Considering this, BioGenix uses exclusively umbilical cord-derived products. Umbilical cord tissue retrieval, which takes place immediately after the umbilical cord is cut upon delivery, is non-invasive and ethically sound. In addition, umbilical cord tissue products have the highest product yield and are the best source of growth factors and cytokines that have an important role in regenerative therapies.
How Regenerative Therapy Works
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